Ensuring Accurate Lab Results in the Era of Biotin Interference and the COVID-19 Pandemic

Tuesday, July 26
7 – 8:30 a.m.
Marriott Marquis, Grand Horizon Ballroom AB
Supported by ABBOTT, Core Diagnostics


One of the most fundamental requirements of the clinical laboratory is to ensure accurate and high-quality test results that advance, diagnose, and/or optimize treatment for patients and communities. With the emerging trends, new diseases, and associated complexities therein, meeting these fundamental needs often requires enhanced awareness and innovative thinking, as well as new evidence-based strategies.

This workshop will highlight relevant evidence that supports the increased use of biotin supplements across the globe while underscoring the associated impact of these trends through published case examples that involve test interference, differences in methodologies, and elevated risks for misdiagnosis across disease areas. Other relevant interferences, such as method differences using hemolyzed samples will also be discussed. Risks have become confounded during the COVID-19 pandemic, as procurement challenges have led to global tube shortages, making accurate and first-pass testing not only crucial, but even more relevant for timely, accurate, and seamless patient care.


By the end of the session, participants should be able to:

  1. Recognize the growing trend related to biotin supplementation, including multiple health benefits.
  2. Appreciate the relationship and risks associated with biotin interference for inaccurate test results and misdiagnosis.
  3. Develop and/or deploy evidence-based strategies to ensure and sustain accurate patient results during the pandemic era and beyond.


Ramani Wondering, MSc, PhD
Scientific Affairs
ABBOTT, Core Diagnostics
North Chicago, IL


Saleh Aldasouqi, MD
Professor of Medicine and Chief of the Division of Endocrinology
Michigan State University
Lansing, MI

James Neuenschwander, MD, FACEP, FASAM
Attending Emergency Physician, Doctors Hospital Columbus Adjunct Associated Professor, The Ohio State University
Columbus, OH